Fight Club - main character in the begining has maybe not SP, but depression definately.
American Beauty - Thora's Birch character seems to have SP and probably depression.
Into the Wild - no sp or anything, but it might be an inspiring movie for all of you and I saw that one guy is already planing to do the same as in this movie.
A Beautiful Mind - main character is a genius who is socially akward.
Late Night Shopping - cool British movie about how comfort zone is bad for us and also one character seems to might have sp and some other problems, epsecially with girls.