I would say it's definitely a possibility. I remember my early stages of S.A. and how I mostly dealt with extreme shyness. As time went on I can remember it branching out into different disorders, like a network or conglomerate of sorts. I mean at one point, I was dealing with S.A. depression, suicidal tendencies, and
agoraphobia all at the same time, I even experienced a few ocd symptoms trying to sneak their way in. Thankfully, these days I don't really suffer from depression, agoraphobia, or suicidal tendencies. S.A. however is still an everyday battle for me, some days I win and unfortunately, some days I take serious loses. The point I'm getting at though is this, I really believe the brain can reconfigure itself when subjected to these disorders over an extended period of time, especially when left untreated. I'm not saying this would make it impossible to overcome, but I do believe this can make much more difficult than if the initial causes had been addressed early on.