I have a massive back ache for many, many years now. And my back feels very weak and stiff. It has caused me to not pursue many things which others do. It has been devastating. But I don't take ANY painkillers because I am glad to have met Doctors here who don't primarily focus on painkillers (a dying breed, no doubt influenced by short term commercial gains instead of holistic treatment). Instead they focus on physiotherapy based exercises. When I do those exercises regularly, it helps, but in my apathy and laziness I soon become irregular with them and I suffer.
But with my indiscipline towards exercising, and not taking any painkillers, I have endured chronic suffering for years on end.