I had to see my GP this afternoon for a routine physical, and it turns out that he also suffers from hyperhidrosis. He is in his early thirties and is a ridiculously smart fellow. We got to talking about the long-term effects of anticholingerics. He is often reluctant to prescribe those that cross the blood-brain barrier to older adults because of problems with memory loss. Here is a link to an article from Science Daily about this:
Using anticholinergics for as few as 60 days causes memory problems in older adults Clonidine and oxybutin both cross the blood-brain barrier; he tends to prescribe these largely for other problems, and high blood pressure and incontinence respectively.
Glycopyrrolate, however, does not bring with it those problems. The biggest risks for regular glyco users, or at least those that suffer from horrible dry mouth, are cavities and gum disease.
Interesting stuff, and probably familiar to most of you who have read up on these.
Using anticholinergics for as few as 60 days causes memory problems in older adults Clonidine and oxybutin both cross the blood-brain barrier; he tends to prescribe these largely for other problems, and high blood pressure and incontinence respectively.
Glycopyrrolate, however, does not bring with it those problems. The biggest risks for regular glyco users, or at least those that suffer from horrible dry mouth, are cavities and gum disease.
Interesting stuff, and probably familiar to most of you who have read up on these.