So, my ETS surgery is booked for the end of June. I've got from now until then to come up with a alternative solution for palmar/plantar HH. I've taken it upon myself to test all the different anticholinergic drugs I can get my hands on, to see what is the best. From my digging around the net I cannot found anyone else who has really explored the variety of different meds on offer. After research, and using my own experiences of Glyco, vesicare, detrunorm and others I've selected a few other to test; benzatropine, Dicyclomine, oxybutinin, probanthine. I'll update my findings so others may benefit, and not waste their time with inexperienced drs and useless meds.
I've got a sneaking suspicion that anticholinergic that are selective of the m1 muscarinic receptor may prove best. Currently drs prescribe meds that have affinity for the m3 receptor (also the same type used for bladder issues), but we'll see.
I've got a sneaking suspicion that anticholinergic that are selective of the m1 muscarinic receptor may prove best. Currently drs prescribe meds that have affinity for the m3 receptor (also the same type used for bladder issues), but we'll see.