In this day and age, there is very little stigma attached to taking "SSRI" medications (lexipro, paxil, prozac, cilexa, welbutrin, zoloft, cimbalta). The number of people on these drugs is pretty astounding. Chances are, if you mention to someone else that you are taking this medication, they will be taking it as well.
But going back to your question, I don't know any close friend or family member who doesn't know I have a prescription. Half of my friends have them too.