How much reliable are researchers' findings about psychiatry and social phobia?!
1) Am J Psychiatry 157:3, March 2000
Low Dopamine D2 Receptor Binding Potential in Social Phobia
2) The Journal of Nuclear Medicine • Vol. 49 • No. 5 • May 2008
Increased Serotonin and Dopamine Transporter Binding in Psychotropic Medication–Naı¨ve Patients with Generalized Social Anxiety Disorder
The above two papers' results are consistent but the following new paper rejects their findings:
3) Depression and Anxiety, 2009
Dopamine transporters, D2 receptors, and dopamine release in generalized social anxiety disorder
Concludes: These findings do not replicate previous findings of altered striatal DAT and D2 receptor availability in GSAD subjects assessed with SPECT. The differences from results of prior studies may be due to differences in imaging methods or characteristics of samples.
1) Am J Psychiatry 157:3, March 2000
Low Dopamine D2 Receptor Binding Potential in Social Phobia
2) The Journal of Nuclear Medicine • Vol. 49 • No. 5 • May 2008
Increased Serotonin and Dopamine Transporter Binding in Psychotropic Medication–Naı¨ve Patients with Generalized Social Anxiety Disorder
The above two papers' results are consistent but the following new paper rejects their findings:
3) Depression and Anxiety, 2009
Dopamine transporters, D2 receptors, and dopamine release in generalized social anxiety disorder
Concludes: These findings do not replicate previous findings of altered striatal DAT and D2 receptor availability in GSAD subjects assessed with SPECT. The differences from results of prior studies may be due to differences in imaging methods or characteristics of samples.
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