Sertraline hydrochloride

Forenote: As we all know everyone is different and respond differently to things. However, I am committed to posting any potential cures for HH.



Sertraline hydrochloride also know as Zoloft is commonly used to treat anxiety and depression. Doctors most commonly prescribe zoloft for HH if they feel your sweating is more "behavioral" or "situational." In other words, they don't necessarily think that you have 'Primary Hyperhidrosis.' Rather, your perspiration is more of a "when 'x' happens, I start sweating profusely."

(note that I suffer from primary HH all over my body.)

Zoloft has some pros in that it has few side effects, is non habit forming, has a cheap generic, does not cause weight gain,and does not change personality.

Zoloft belongs to a class of drugs known as SSRIs (selective serotonin reuptake inhibitors). Zoloft works to correct a chemical imbalance in the brain. While it is unknown exactly what symptoms these chemical imbalances can relieve (it is known to help with anxiety and depression) I as well as my doctor speculate that Zoloft can help people who have an overactive sympathetic nervous system (OSNS).

OSNS is thought to be the cause of HH, and while I have tried every cure under the rainbow including ionto, glyco, beta-b, botox, drysol, I have recently started to try Zoloft.

To test its effects on HH the doctor prescribed me a low dose, 25mg. 25mg is thought to be an ineffective dose when treating anxiety and depression, however we were curious to see the effects on HH. When taking Zoloft it can take up to 8 weeks for the effects to be noticed and after about 4 weeks a mysterious effect started happening to me one day. When walking in 95F heat I was shocked to find my feet were not sweating in my shoes and my body was not sweating at all! Thus far, I have had very little sweating all over my body.

Though I currently have botox injections in my hands and use Professional Right Guard Deodorant, my feet, back, face, buttocks have not sweat at all.

I recommend everyone to talk to their doctors and look into trying Zoloft for themselves. I will continue to update everyone on how it works. If things continue like this, I will continue taking Zoloft.

Regards,

C

Zoloft is no different than any other SSRI, its just a crap shoot whether the drug works or not.

I was on paxil CR and regular paxil for years. I still sweated my balls off. Problem with that was I got fat too.

Paxil is a Paroxetine

im aware of that. zoloft has the same side effects though.

Zoloft does not cause weight gain though.......

Maybe not for you. Do a little research and you will find it does for most.

Over more than six months of sertraline therapy for depression, patients showed an insignificant weight increase of 0.1%.[126] Similarly, a 30-month-long treatment with sertraline for OCD resulted in a mean weight gain of 1.5% (1 kg).[127] Although the difference did not reach statistical significance, the weight gain was lower for fluoxetine (Prozac) (1%) but higher for citalopram (Celexa), fluvoxamine (Luvox) and paroxetine (Paxil) (2.5%). Only 4.5% of the sertraline group gained a large amount of weight (defined as more than 7% gain). This result compares favorably with placebo, where, according to the literature, 3–6% of patients gained more than 7% of their initial weight. The large weight gain was observed only among female members of the sertraline group; the significance of this finding is unclear because of the small size of the group.[127]

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Less than .1% weight gain...

I want to try something like this but I'm not sure I want to go on happy pills to cure my hand sweat. Seemed like a bad connection waiting to happen since I'm not depressed about anything.

MyHyperhidrosis said:

I want to try something like this but I'm not sure I want to go on happy pills to cure my hand sweat. Seemed like a bad connection waiting to happen since I'm not depressed about anything.

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You should try it after exhausting other remedies. This is not a happy pill either........

Is it still working ?

hb72 said:

Is it still working ?

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Yes, but I still want to see if it working in the next 1-2 months. I'll let everyone know.

Because my sweating was only reduced and I felt like I could achieve even more of a reduction the doctor has moved the dosage up to 50mg a day. It will take 4-8 weeks to start noticing the effects of this. I will keep everyone posted.

Ok, my doc just gave me a script to this and said it would help with excessive sweating if it was caused by some kind of underlying anxiety. Before I start taking it, I would like an update. Have you gained any weight?

So much dysinformation, so little time --

Zoloft is an SSRI, yes. But it is a unique chemical compound in an area of medical knowledge which constantly proclaims, "The exact mechanism is unknown."

MOST people report that Zoloft (sertraline) is an upper for them. Your mileage may vary.

FWIW, Paxil IS paroxetine. There is no class of drugs which are called "paroxetines."

And finally, sertraline (Zoloft) made me sweat more than any other SSRI, though they all make me sweat more than usual.

After being on Zoloft since my first post I have found not weight gain and a reduction in sweat. It has helped me lower my anxiety and in turn help me with my sweating. I am glad I am on it and would not change. I still sweat tho so i also use Ionto with glyco based water mix and take Sweatosan N daily.