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I'm a newbie to the forum. Could somebody pls tell me what's the best medicine to take ahead of a presentation or a meeting? And would it be available over the counter

I'm trying to identify situations where I am uncomfortable with a view to devising solutions. The one on my mind now is when I'm in a group of 3 or more people (but not more than 5 or 6), and the others start a conversation about something that has no connection or relevance to me. For eg, they...